Critical interpretation and design of health research: Glossary

Key Points

Workshop 1: Critical Reading of Health Literature
  • Arguments have facts plus reasoning plus persuasion

  • Explanations have facts plus reasoning no persuasion

  • Non-arguments do not have reasoning embedded in them

Workshop 1, part II: Constructing standard form
  • Explicit arguments are directly expressed

  • Implicit arguments have to be inferred from explicit arguments

  • Standard form provides an argument map

Workshop 2: Deductive, inductive, and abductive reasons
  • Deductive reasoning is about logic

  • Inductive reasoning is about finding patterns and probability

  • Abductive reasoning is about explanations

  • In abductive reasoning, you ask the question:why?

  • Start with an explanation

  • Your theory is an abstract form of explanation

  • Derive hypotheses from theory

  • Your theory must explain everything observed, nothing left

  • You must have more than one theory to test

  • Either find an exceptional observation that refutes the theory

  • Or find a simpler theory to work with

  • Correlation does not imply causation

  • Valid association plus causal conditions = causation

  • Valid association = chance, bias, and confounding

  • Null hypothesis significance testing is about chance

  • You can only fix bias issues before the study begins

Workshop 3: Epidemiological study designs
  • Case series, case control studies, cohort studies are commonly used epidemiological study designs

  • Case control studies are great for cancer & other rare diseases

  • Cohort studies are great for rare exposure but common diseases

Workshop 4: biases
  • Biases are systematic errors in study designs

  • Biases should be eliminated at the stage of study designs

  • Biases will drive the results of studies either towards the null or in unpredictable directions

Workshop 5: how to write a proposal
  • Study proposals have three elements: background, review of literature, and methods

  • In background, introduce the main concept and the gaps in the literature

  • In the methods section, lay out the steps you will take to complete the study

Glossary

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